GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs10935120 | 1 | rs9832785 | chr3:134213070 | CEP63 | chr3:134204575-134293852:+ | 0.4 | 5.81 | 8.19E-8 | Height |
| THYM | cis | rs9815354 | 1 | rs9834098 | chr3:41833493 | ULK4 | chr3:41288091-42003660:- | 1 | 10.44 | 1.92E-17 | Diastolic blood pressure |
| THYM | cis | rs10935120 | 1 | rs9834755 | chr3:134206845 | ANAPC13 | chr3:134196547-134204865:- | 0.58 | 7.98 | 3.28E-12 | Height |
| THYM | cis | rs10935120 | 1 | rs9834755 | chr3:134206845 | CEP63 | chr3:134204575-134293852:+ | 0.4 | 5.9 | 5.49E-8 | Height |
| THYM | cis | rs10935120 | 1 | rs9835204 | chr3:134261342 | ANAPC13 | chr3:134196547-134204865:- | 0.58 | 8.01 | 2.88E-12 | Height |
| THYM | cis | rs10935120 | 1 | rs9835204 | chr3:134261342 | CEP63 | chr3:134204575-134293852:+ | 0.41 | 6.04 | 2.93E-8 | Height |
| THYM | cis | rs9876781 | 1 | rs9838618 | chr3:48487353 | TREX1 | chr3:48501186-48509043:+ | -0.29 | -4.36 | 3.23E-5 | Longevity |
| THYM | cis | rs9815354 | 1 | rs9838965 | chr3:41927938 | ULK4 | chr3:41288091-42003660:- | -1.02 | -11.47 | 1.22E-19 | Diastolic blood pressure |
| THYM | cis | rs9815354 | 1 | rs9839399 | chr3:41928044 | ULK4 | chr3:41288091-42003660:- | -1.02 | -11.47 | 1.22E-19 | Diastolic blood pressure |
| THYM | cis | rs9815354 | 1 | rs9840037 | chr3:41827522 | ULK4 | chr3:41288091-42003660:- | 1 | 10.44 | 1.92E-17 | Diastolic blood pressure |
| THYM | cis | rs9815354 | 1 | rs9840532 | chr3:41885697 | ULK4 | chr3:41288091-42003660:- | 0.97 | 10.79 | 3.37E-18 | Diastolic blood pressure |
| THYM | cis | rs10935120 | 1 | rs9841212 | chr3:134191938 | ANAPC13 | chr3:134196547-134204865:- | 0.54 | 7.49 | 3.5E-11 | Height |
| THYM | cis | rs10935120 | 1 | rs9841212 | chr3:134191938 | CEP63 | chr3:134204575-134293852:+ | 0.38 | 5.62 | 1.87E-7 | Height |
| THYM | cis | rs984222 | 1 | rs984222 | chr1:119503843 | WARS2 | chr1:119573841-119683295:- | -0.56 | -6.63 | 2.0E-9 | Waist-to-hip ratio adjusted for body mass index;Waist-hip ratio |
| THYM | cis | rs9815354 | 1 | rs9842261 | chr3:41822708 | ULK4 | chr3:41288091-42003660:- | -1.06 | -8.02 | 2.67E-12 | Diastolic blood pressure |